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Which is considered the first line drug used to treat mania? Current practice guidelines state that first - line treatment for severe manic or mixed episodes is either lithium plus an antipsychotic or valproate plus an antipsychotic; while for less ill patients, monotherapy with lithium, valproate, or an antipsychotic may be sufficient.
Is there a mood stabilizer that doesn't cause weight gain? Mood stabilizers used to treat bipolar disorder include lithium (Lithobid), valproic acid (Depakene), divalproex sodium (Depakote), carbamazepine (Tegretol, Equetro, others) and lamotrigine (Lamictal). All of these medications are known to increase the risk of weight gain except lamotrigine.
What happens if you leave bipolar untreated? When bipolar disorder symptoms are untreated, you risk suffering more severe episodes of major depression and hypomania or mania. In addition, there are high death rates from heart disease, stroke and cancer that are associated with untreated bipolar symptoms. Bipolar disorder does not go away on its own.
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